N-T-boc-L-glutamic acid A-T-butyl-ester - Names and Identifiers
N-T-boc-L-glutamic acid A-T-butyl-ester - Physico-chemical Properties
Molecular Formula | C14H25NO6
|
Molar Mass | 303.35 |
Density | 1.121±0.06 g/cm3(Predicted) |
Melting Point | 111.0 to 115.0 °C |
Boling Point | 449.8±40.0 °C(Predicted) |
Flash Point | 225.8°C |
Solubility | Soluble in dimethyl formamide. |
Vapor Presure | 2.42E-09mmHg at 25°C |
Appearance | Crystalline powder |
Color | White to Almost white |
BRN | 3653769 |
pKa | 4.48±0.10(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
Refractive Index | 1.47 |
MDL | MFCD00038273 |
N-T-boc-L-glutamic acid A-T-butyl-ester - Risk and Safety
Risk Codes | R22/22 -
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S4 - Keep away from living quarters.
S7 - Keep container tightly closed.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S35 - This material and its container must be disposed of in a safe way.
S44 -
|
WGK Germany | 3 |
HS Code | 2924 19 00 |
N-T-boc-L-glutamic acid A-T-butyl-ester - Introduction
N-T-boc-L-glutamic acid A- T-butyl-ester(N-T-boc-L-glutamic acid A- T-butyl-ester) is an organic compound. Its chemical formula is C15H25NO6 and its molecular weight is 315.36g/mol.
Nature:
N-T-boc-L-glutamic acid A- T-butyl-ester is A solid crystal, soluble in organic solvents such as methanol, ethanol and methylene chloride, insoluble in water. It can form a single crystal, the structure of which is usually determined by X-ray crystallography. The compound is stable at room temperature.
Use:
N-T-boc-L-glutamic acid A- T-butyl-ester is commonly used as A protecting group in organic synthesis. It can protect the carboxyl group (COOH) of glutamic acid to prevent unwanted side reactions in chemical reactions. The protecting group can be easily removed by an appropriate method when necessary to obtain the original glutamic acid compound.
Method:
The method of preparing N-T-boc-L-glutamic acid A- T-butyl-ester is usually carried out through synthetic organic chemical reactions. First, under the protection of nitrogen, tert-butoxycarbonyl-L-glutamic acid is reacted with tert-butyl magnesium bromide to generate an intermediate; Then, it is reacted with sodium bicarbonate to generate a final product, that is, N-T-boc-L-glutamic acid A- T-butyl-ester.
Safety Information:
N-T-boc-L-glutamic acid A- T-butyl-ester is generally relatively safe under regular chemical laboratory operating conditions. However, because it is an organic compound, it is still necessary to use appropriate personal protective equipment in chemical laboratories, such as laboratory gloves, goggles and protective clothing. In addition, the relevant laboratory safety procedures should be followed.
Last Update:2024-04-10 22:29:15